Study SRP001386 Download

TitleGlobal survey of escape from X inactivation by RNA-sequencing in mouse
AbstractX inactivation equalizes the dosage of gene expression between the sexes, although some genes escape silencing. We performed RNA-sequencing in Mus musculus x Mus spretus cells, relying on expression of SNPs to discriminate allelic origin. We found 15/387 (4%) mouse genes with significant expression from the inactive X, including 10 novel escape genes. We estimate that mice have significantly fewer escape genes compared with humans.
Referencesno content
OrganismsMus spretus
Descriptionno content
SubmitterUniversity of Washington
Related objects